incidence of vitamin B12 and vitamin D deficiency in urban South Indian population, and to evaluate the association of various cardiometabolic risk factors with vitamin B12 and vitamin D deficiencies. The overall prevalence of vitamin B12 and vitamin D deficiency were found to be 14.9% and 84%, respectively. The highest prevalence of vitamin B12, vitamin D, and folic acid deficiencies were observed among diabetic individuals, followed by those with prediabetes and normal glucose tolerance. Additionally, vitamin B12 deficiency was associated with a higher prevalence of hypertriglyceridemia. Vitamin D deficiency was associated with a higher prevalence of abdominal and general obesity, as well as metabolic syndrome.